Functional research on NMN

Nicotinamide Mononucleotide (NMN) is a natural biologically active nucleotide and one of the key precursors to generate nicotinamide adenine dinucleotide (NAD+). NAD+ is a coenzyme of redox and is widely involved in cells. Energy metabolism, DNA repair, signal transduction and other biological functions play an important role in the energy of biological cells.

NMN can increase NAD+ levels in the body and exert its functions through NAD+. Studies have found that NMN can enter the blood within 2 to 3 minutes after supplementation, increase the NMN content in tissues within 15 minutes, and quickly increase the NAD+ level in the body to exert its functions.

In recent years, studies have shown that NMN has a good effect on intestinal health, cardiovascular and cerebrovascular diseases, neurodegenerative diseases, and delaying aging. In addition, NMN can also regulate endocrine in the body, increase insulin secretion, and prevent and treat obesity and diabetes.

Functional research on NMN:

1. NMN can increase the abundance of butyrate-producing bacteria and other probiotic bacteria, reduce the abundance of harmful bacteria, reduce the permeability of intestinal mucosa, and protect intestinal function;

2. NMN can exert anti-aging functions by increasing NAD+ levels. NMN can significantly reduce senescent cells in aging mesenchymal stem cells by improving the mitochondrial function of cells, and has the effect of inhibiting the aging of mesenchymal stem cells;

3. NMN can reverse the age-related insufficient systolic function under high cardiac load by increasing the NAD+ content under high cardiac load;

4. Research has found that when NMN levels are increased, the availability of NAD+ increases, increasing the mitochondrial oxygen consumption rate, reducing the tendency of mitochondrial fission, and causing the hippocampus region of mitochondria to produce longer mitochondria, thus improving the respiratory function of mitochondria, which is beneficial to the treatment of Alzheimer's disease. Heimer's disease.

In summary, it can be seen that NMN has a good therapeutic and repairing effect on neurodegenerative diseases and aging degenerative diseases. Therefore, NMN is widely used in medical and functional foods.

NMN is a key precursor substance for generating NAD+. Its function is reflected by NAD+. It has the effect of antioxidant and reducing oxidative stress, especially in anti-aging. In recent years, relevant research has fully demonstrated its good performance in the treatment of some specific diseases, such as cardiovascular disease, Alzheimer's disease, Parkinson's disease, obesity, etc. NMN is an endogenous substance in the human body and is highly safe, and measures are in place to ensure its stability in the body.

Tag: NMN

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