New ideas for hangover relief, Why don't you try NMN?

Drinking has a long history, and as the old saying goes, "one drink solves a thousand sorrows."

Wine is a necessary thing for parties, is a close friend to relieve worries, but excessive drinking can cause no small trouble to our bodies.

Such as alcoholic liver, cirrhosis, liver fibrosis and even liver cancer.

Studies have shown that NMN has the effect of relieving alcohol and protecting the liver. Do you want to know about it quickly?

NMN does have a certain effect in hangover relief, mainly due to its function as NAD+.

NAD+ is an essential substance in the process of alcohol metabolism, and alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) involved in our body need to combine NAD+ to play a role.

We need to understand how alcohol is metabolized in the body.

After alcohol enters the body, it is mainly metabolized by the liver.

Alcohol dehydrogenase in the liver converts alcohol into acetaldehyde, which is then converted by acetaldehyde dehydrogenase into acetic acid, which is finally excreted from the body.

In this process, NMN can accelerate the decomposition and metabolism of alcohol by enhancing the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase, thus reducing the damage of alcohol to the liver.

NMN plays an important role in the protection of liver cells.

Harmful substances such as acetaldehyde produced during alcohol metabolism can cause damage to liver cells.

NMN is able to reduce the production of these harmful substances and accelerate their excretion from the body, thereby protecting liver cells from damage.

As a precursor of NAD+ (nicotinamide adenine dinucleotide), NMN can enhance the level of NAD+ in cells, thereby regulating the process of energy metabolism and improving the metabolic disorders caused by alcohol.

Taking NAD+ precursor substance NMN (Nicotinamide Mononucleotide) can rapidly increase the content of NAD+ in the liver, accelerate the catabolism of alcohol, and thus play a rapid role in hangover. However, more important than "hangover" is "liver protection".

In 2019, a study by the University of Colorado in the United States allowed NMN to unlock the "liver protection" efficacy.

When mice with alcoholic liver disease were fed 500mg/kg of NMN every other day, levels of NAD+ and a range of precursors returned to control levels.

Moreover, NMN prevented the increase of two biomarkers of liver injury in plasma, ALT (alanine aminotransferase) and AST (aspartate aminotransferase).

This suggests that NMN has a protective effect on ethanol-induced liver injury.

They also found through RNA sequence analysis that ethanol significantly altered the expression of 1,778 genes, while NMN treatment attenuated the effects of ethanol on 25% (437) of these genes.

This study found that NMN not only increased the level of NAD+ in the liver of experimental mice, but also had a protective effect against ethanol (alcohol) induced liver injury.

Taking NAD+ precursor NMN can rapidly increase the content of NAD+ in the liver and accelerate the catabolism of alcohol, thus playing a rapid role in hangover.

It has protective effect on liver injury induced by alcohol.

Tag: NMN

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