Preparation and Advantages of Citicoline Sodium

The chemical name of Citicoline sodium is monosodium salt of choline cytosine nucleoside diphosphate, CAS: 33818-15-4, and Citicoline Sodium is the sodium salt of citicoline, which is a kind of It is a drug raw material for improving cognitive function, and its indication is to treat neurological sequelae caused by craniocerebral injury or cerebrovascular accident.

Preparation of Citicoline Sodium:

There are many methods for preparing citicoline sodium, but they can be roughly classified into three ways. One is the organic chemical synthesis method, which has problems such as difficult separation of the product from the condensing agent, unsuitability for medicinal use, low reaction conversion rate, many by-products, high cost, and serious environmental pollution; the other is the microbial fermentation method, which utilizes yeast , Escherichia coli and other engineering bacteria for fermentation, this method has problems such as low product concentration and unstable yield; there is also an enzymatic synthesis method, which uses enzymes to carry out biosynthetic reactions. This method is green and environmentally friendly, and it is currently a hot spot developed by the company .

Compared with other drugs that improve cognitive function, citicoline sodium has the following advantages:

1. High security. It has less toxic and side effects on the human body, and the common adverse reactions are mild gastrointestinal discomfort with a short duration.

2. Improve memory: It can promote the proliferation and regeneration of brain cells, thereby improving memory and learning ability.

3. Improve attention and concentration: enhance the signal transmission between brain neurons, improve attention and concentration.

4. Alleviate mild cognitive impairment: Assist in alleviating mild cognitive impairment and help improve the quality of life of the elderly.

5. Convenient and easy to use: Citicoline Sodium has high bioavailability, both tablets and injections have high absorption rate, and can be made into Citicoline Sodium Tablets, Citicoline Sodium for Injection, Citicoline Sodium Sodium capsules, etc. Once citicoline sodium is absorbed, it can be widely distributed in various parts of the body, and it can pass through the blood-brain barrier and enter the central nervous system.

Tag: Citicoline Sodium

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