β-Nicotinamide Mononucleotide transferase reaction product

NMN (Nicotinamide Mononucleotide) is the product of nicotinamide phosphoribosyl transferase reaction and is one of the key precursors of NAD+. In mammals, NMN is produced by nicotinamide under the catalysis of Nampt,β-Nicotinamide Mononucleotide and then NMN is produced under the catalysis of nicotinamide mononucleotide adenosyltransferase to produce NAD+NMN in the human body by converting into NAD+ to perform its physiological functions,β-Nicotinamide Mononucleotide such as Activate NAD+substrate-dependent enzyme Sirt1 (histone deacetylase,β-Nicotinamide Mononucleotide also known as sirtuin), regulate cell survival and death, maintain redox state,β-Nicotinamide Mononucleotide etc. Recent studies have found that by regulating the level of NMN in the organism, it has a better therapeutic and repairing effect on cardiovascular and cerebrovascular diseases, neurodegenerative diseases and aging degenerative diseases; in addition,β-Nicotinamide Mononucleotide NMN can also play a role in participating in and regulating the body’s endocrine. To protect and repair pancreatic islet function,β-Nicotinamide Mononucleotide increase insulin secretion, prevent and treat metabolic diseases such as diabetes and obesity.

The biological activity of NMN 1.1 NMN alleviates and ameliorates ischemic heart and brain tissue damage,β-Nicotinamide Mononucleotide and the therapeutic effect of NMN on stroke. Stroke is an acute cerebrovascular disease caused by blood circulation disorders in the brain. It has high mortality and The disability rate seriously threatens human health.

Studies have found that NMN can protect brain nerves and promote blood vessel and nerve regeneration by activating the Nampt-NAD+ defense system. It has a good protective effect on cerebral hemorrhage and nerve damage caused by cerebral hemorrhage transformation. It is a potential anti-stroke treatment drug. Through the analysis of the metabolic process of NMN in brain tissues, it was found that NMN prevents neuronal cell apoptosis induced by cerebral ischemia by improving the bio-energy metabolism of the tissue after ischemia,β-Nicotinamide Mononucleotide and promotes nerve regeneration after cerebral ischemia. Sexual brain injury has a strong protective effect. For hemorrhagic brain injury,β-Nicotinamide Mononucleotide increasing the level of NMN can reduce the hemoglobin content in the infarct tissue, reduce bleeding and edema,β-Nicotinamide Mononucleotide and reduce the oxidative toxicity damage of the brain tissue caused by oxidative stress.

Tag: Β-Nicotinamide Mononucleotide

Supplier Introduction: China glutathione supplier and NMN manufacturer GSHworld, the company mainly develops biotechnology and industrialization. As a global pioneer in enzymatic catalytic ATP regeneration technology, our company advocates green production and is committed to providing customers with better and more environmentally friendly products and services. Glutathione Manufacturer,NMN Factory,Citicoline Sodium supplier,China NMN manufacturers