High Purity Dasatinib Intermediate Raw Material CAS 302964-08-5 for Dasatinib API

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Nicotinamide Mononucleotide ("NMN", "NAMN", and "β-NMN") is a nucleotide derived from ribose and nicotinamide. Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). In mice, NMN enters cells via the small intestines within 10 minutes converting to NAD+ through the Slc12a8 NMN transporter. Because NADH is a cofactor for processes inside mitochondria, for sirtuins, and for PARP, NMN has been studied in animal models as a potential neuroprotective and anti-aging agent.Dietary supplement companies have aggressively marketed NMN products claiming those benefits.Doses of up to 500 mg was shown safe in men in a recent human studyat Keio University School of Medicine, Shinjuku, Tokyo Japan. Multiple long-term human studies are underway

Application

1,Nicotinamide mononucleotide , it involved in intracellular NAD (nicotinamide adenine dinucleotide, cell energy conversion important coenzyme) synthesis, used in anti-aging, fall blood sugar and other health care products,nmn aging.

2,Nicotinamide has prevention and treatment of heart block, sinus node function and anti-fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.

3,Nicotinamide Mononucleotide is a water-soluble vitamin, The product is white crystalline powder, odorless or nearly odorless, bitter in taste, freely soluble in water or ethanol, dissolvable in glycerin.

4.Nicotinamide Mononucleotide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.nicotinamide mononucleotide human trials is not yet finished.

Product Properties

CAS No.: 1094-61-7

Formula: C₁₁H₁₅N₂O₈P

Appearance: White or almost white powder

Appearance of solution: Clear and colorless

pH value of solution: 2~3

Heavy metals: Not more than 10ppm

Purity ( HPLC ): 98.0% ~ 100.0%

Loss on drying: Not more than 1%

Packing and transportation

Package detail:1kg/aluminum foil bag;20Kgs in Cardboard drum with two-plastic bags inside

Transportation:

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