Mechanism Of Action Of Citicoline Sodium

Citicoline sodium is mainly used clinically to treat a variety of neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, etc. Studies have also shown that citicoline can increase the brain's uptake of dopamine and glutamate, thereby improving cognitive performance.

Citicoline is an essential substance for cell membrane structural phospholipids, and has been found to have neuroprotective effects in patients with neurological diseases. In clinical stroke trials, citicoline was also found to be the only neuroprotective agent to demonstrate safety and sustained beneficial effects in acute ischemic stroke through confirmatory clinical trials.

Mechanism of action:

1. Protect the lipid structure of the cell membrane;
2. Stimulate the neurotransmitter system;
3. Promote the energy metabolism of brain tissue.
Efficacy: By reducing cerebrovascular resistance and increasing cerebral blood flow, it can promote brain substance metabolism and improve cerebral circulation. In addition, Citicoline Sodium can enhance the function of the ascending activation system of the brainstem reticular structure, enhance the function of the pyramidal system, and improve motor paralysis, so it has a certain effect on promoting the recovery of brain function and awakening.

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