Pure NMN Active Pharmaceutical Ingredient

NMN can increase the level of NAD+ in animals and exert its function through NAD+. Studies have found that NMN can enter the blood within 2 to 3 minutes after supplementation, and enhance tissue

Increase the NMN content in the body, and rapidly increase the level of NAD+ in the body to exert its functions, such as activating lysine deacetylase with NAD+ as the only substrate, regulating the process of cell survival and death, and maintaining the intracellular redox state. Recent studies have shown that regulating the level of β-NMN in organisms can have a good effect on intestinal health, cardiovascular and cerebrovascular diseases, neurodegenerative diseases, and delay aging. In addition, NMN can also participate in regulating the body's endocrine, increasing Insulin secretion, thereby preventing the occurrence of obesity and diabetes.

The basic functions of the gut microbiota include facilitating digestion and absorption of food, synthesizing essential vitamins, eliminating toxic compounds, resisting pathogens, maintaining the integrity of the intestinal cell layer, and regulating immunity, among others. If the intestinal lining is damaged and the intestinal flora is unbalanced, the microbiota will invade the intestinal lining cells (mucosal cells), affecting lipid absorption and storage. These changes may lead to metabolic diseases, such as obesity, type Ⅱ diabetes and non-alcoholic fatty liver. Huang Pan et al. found that long-term NMN treatment increased the abundance of butyrate-producing bacteria and other probiotics, decreased the abundance of several harmful bacteria, and reduced the permeability of the intestinal mucosa, which has a positive effect on protecting intestinal function. 

In recent years, relevant studies have shown that NMN is related to various diseases such as diabetes, obesity, and Alzheimer's disease. Therefore, the development of drugs with NMN as an active ingredient has become a hot spot in the medical field. Imai S. et al. in the United States disclosed a drug with NMN as an active ingredient for improving age-related diseases such as obesity, hyperlipidemia, diabetes, and decreased memory function. In the treatment of diabetic nephropathy, Ito Yu and others in Japan invented a medicament with MNM as the main active ingredient and proved its administration method. Tomomi Saeki of Japan invented a complex of β-NMN and yeast extract, which has the effect of preventing or improving diabetes, especially type Ⅱ diabetes and various complications caused by diabetes.

F&A

1.What certificates do you have?

ISO,Kosher,Halal,FDA,Business License and Food Management License.

2.How to control and quality assurance?

a.High grade clean workshop.

b.Inspection center equipped with instruments of HPLC,GF etc,R&D and QC for testing of each batch.

c.Cooperated with third-party test agency for testing heavy metals,pesticide residues,allergen etc.

3.What’s your shipping methods and delivery time?

a.Shipping Methods:DHL,UPS,TNT,FEDEX,EMS

b.Shipping time:5-8 days by air or 20-40 days by sea.

4.How about delivery leadtime?

Within 7 working days after payment confirmed.