The Medical Functions Of S-Adenosyl-L-methionine

S-Adenosyl-L-methionine(SAMe) is a natural active substance present in the body. As the most important methyl donor in the body, SAMe can participate in important biochemical reactions in the body through transmethylation, transsulfation and transaminopropyl. It can be used to treat various liver diseases such as cholestasis, drug-induced liver injury and alcoholic liver disease, and can significantly improve the depressive symptoms associated with liver diseases. In addition, SAMe also has other therapeutic effects such as anti-tumor and anti-inflammatory.

Function

SAMe is widely used in the treatment of liver diseases caused by various factors through transmethylation, transsulfurization and transaminopropyl effects, in the treatment of acute and chronic viral hepatitis, alcoholic liver disease, intrahepatic cholestasis of pregnancy, etc. All have good curative effect. In addition, it plays an important role in improving the bad mood of patients with liver disease and treating liver disease complicated with depression. With further in-depth clinical research, the therapeutic effects of SAMe on arthritis, Parkinson's disease, Alzheimer's disease, migraine, epilepsy and insulin resistance have gradually attracted attention. SAMe preparations mainly include enteric-coated tablets and injections. Enteric-coated tablets are used as oral preparations for long-term treatment and have more economic advantages.

Application

1. SAMe generates phosphatidylcholine and methylated phospholipids through transmethylation, which is beneficial to improve the fluidity of cell membranes and promote bile excretion. At the same time, SAMe can also protect the integrity of the cytoskeleton. SAMe participates in the generation of cysteine and glutathione in hepatocytes through transsulfation, promotes the uptake of bile acids in hepatocytes, improves the detoxification of bile acid metabolism system, and can prevent or reduce the effect of oxygen free radicals on the liver. Cell damage, thereby reducing jaundice, reducing enzymes and promoting liver cell regeneration;

2. It can effectively treat cholestasis of pregnancy and significantly improve the itching symptoms and liver function of patients;

3. It has similar efficacy to tricyclic antidepressants, and is a safe and effective natural antidepressant, with fast onset and few adverse reactions, and is suitable for patients with chronic liver disease complicated by depression;

4. It also has anti-inflammatory, analgesic and tissue regeneration functions, and can be used to treat knee osteoarthritis.

The high-quality pharmaceutical raw materials come from SHENZHEN GSH BIO-TECHNOLOGY CO., LTD.'s continuous exploration and pursuit of technology. The company has established a professional R&D center in Beijing, China for product research, development, formulation, testing, testing and other high-tech content At the same time, it has established three production bases in Anhui and Jilin, China, and built modern workshops that meet the GMP standards for pharmaceuticals.

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