H1N1 virus is so strong, can NMN help?

With the change of seasons, respiratory diseases enter a high incidence period, infectious diseases such as influenza A (H1N1) and mycoplasma pneumonia often cause serious lung damage and inflammation, threatening the health of patients.

Recent research suggests that niacinamide mononucleotide (NMN), as a dietary supplement, may play an important role in preventing and alleviating lung damage and inflammation caused by these diseases.

Relationship between NMN and immune system

NMN is a precursor to NAD+ (nicotinamide adenine dinucleotide) in the body, which is essential in cellular metabolism and energy production.

Studies have shown that supplementing NMN can significantly improve the vitality and number of immune cells (such as natural killer cells and lymphocytes), and enhance the body's defense ability against viruses, bacteria and other pathogens.

For example, a study published in Cell Metabolism found that NMN supplementation boosted immune function in mice, significantly increasing their resistance to influenza viruses.

Effect of NMN on lung health

A team of researchers at West China Hospital of Sichuan University has published an important study in the journal MedComm that explores the role of NMN in lung health.

The study found that supplementation with NMN or NR (nicotinamide ribose) was able to increase the synthesis of NAD+, enhance the activity of Sirt1 (silencing message regulator 1), maintain mitochondrial function, protect nuclear DNA integrity, and exert anti-inflammatory and antioxidant effects.

These mechanisms work together to help resist replication and stress-induced cellular senescence and promote lung health.

Application of NMN in mycoplasma pneumonia

Mycoplasma pneumonia is a respiratory infection caused by mycoplasma pneumoniae that often leads to inflammation and damage to the lungs.

Studies have shown that NMN supplementation can significantly increase the activity and number of immune cells, enhance the body's ability to clear pathogens such as mycoplasma, and thus reduce lung inflammation and damage.

Clinical research and prospect

Although current clinical studies on NMN in the prevention and treatment of lung damage and inflammation caused by swine flu and mycoplasma pneumonia are still ongoing, initial results are encouraging.

With further research, NMN is expected to be an effective adjunct therapy to help reduce lung damage and inflammatory responses caused by respiratory infections.

How can I prevent it?

During the high respiratory disease season, it is essential to maintain good personal hygiene practices, such as frequent hand washing, wearing masks, avoiding close contact with infected people and strengthening immunity.

As a potential immunomodulator, NMN may play a positive role in preventing and slowing lung injury and inflammation caused by swine flu and mycoplasma pneumonia.

Reference material

[1] Matthay, M. A., & Zemans, R. L. (2011). The acute respiratory distress syndrome: pathogenesis and treatment. Annual review of pathology, 6, 147.

[2] Tian, Y., Zhu, C. L., Li, P., Li, H. R., Liu, Q., Deng, X. M., & Wang, J. F. (2023). Nicotinamide Mononucleotide Attenuates LPS-Induced Acute Lung Injury With Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects. Journal of Surgical Research, 283, 9-18.

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