NMN benefits you may not aware

With the passage of time, the years are merciless, and people are searching for the secret weapon that can race time. Fortunately, the Nicotinamide Mononucleotide, or NMN, which has been widely discussed in recent years, may provide us with a new idea to overcome this difficulty.

NAD+ "Gas Station"

Before discussing the ideas, let's talk about NMN,NMN is actually an important intermediate product of the synthesis of NAD+ coenzyme necessary for human body, and NAD+ plays a key role in many biological reactions, such as maintaining DNA repair function, resistance to oxidative stress, etc., it is indispensable to participate in.

With age, the level of NAD+ in the body gradually decreases, which leads to physical decline and various diseases.

Increasing the level of NAD+ has become an important strategy for anti-aging and treatment of related diseases.

What is the magic effect of NMN?

NMN has been shown to be effective in animal model experiments for various diseases:

Published in the journal Science in 2021. A 10-week randomized, placebo-controlled, double-blind trial conducted by Samuel Klein's team at the University of Washington evaluated the effects of NMN supplementation on metabolic function in postmenopausal women with overweight or obesity. Results showed that NMN can increase of pre-diabetes is overweight or obese women muscle insulin sensitivity and insulin signal transduction and reshaping.

The application of NMN in anti-aging research is no less important, and a study at Harvard Medical School found that supplementing NMN can extend the lifespan of mice by targeting SIRT2 pathway through NAD+, and enhance the oxidative metabolism capacity of skeletal muscle.

The "universal oil" of daily life

Even in everyday life, NMN is capable of exerting incredible capabilities, and worldwide, obesity is a growing epidemic that is more likely to develop into metabolic diseases characterized by increased obesity, insulin resistance, high blood sugar levels, high blood pressure and dyslipidemia.

These individuals are also at higher risk for type 2 diabetes, cardiovascular disease, non-alcoholic fatty liver disease, atherosclerosis, stroke and cancer as a result.

Obesity is also associated with accelerated aging and shorter life expectancy. And long-term supplement NMN can significantly inhibit the weight gain associated with age, lower the quality of fat, improve insulin sensitivity.

NMN, your gut gardener

According to the 2012 national intestinal health white paper, about 95% of americans have bowel problems. Among them, constipation, bad breath, bloating and indigestion have become the high-frequency intestinal problems plaguing people.

Most of the intestinal problems are closely related to the imbalance of intestinal flora, such as the disturbance of life and rest, poor eating habits, eating spoiled food, changes in the external environment, drug abuse and psychological stress, etc., may lead to the imbalance of intestinal flora.

NMN can also treat intestinal disorders

1. Liver disease:

In May 2022, a research team from Tsinghua University published research results in Cells: NMN can improve the protein acetyl group in the liver of elderly mice.

Simply put, the acetylation of aging-related proteins increases across the board in the elderly liver, and NMN prevents this increase in just 4 weeks.

2. Intestinal diseases:

In July 2021, jiangsu university school of medicine researchers in the journal of the Frontiers in Nutrition about "NMN by adjusting the gut microbiota to maintain steady state" of the study, found that NMN had regulation of intestinal flora.

NMN may be a new way to regulate intestinal flora and solve intestinal problems.

3. Pancreatic diseases:

A study in the British Journal of Pharmacology showed that fecal transplantation improves the intestinal flora imbalance, thereby increasing the level of NMN metabolism, promoting the synthesis of NAD+, and then activating Sirt3 protein, alleviating pancreatic tissue damage and inflammatory response, and achieving the purpose of improving acute pancreatitis.

Direct NMN supplementation can also reduce the symptoms of acute pancreatitis.

NMN is in the future

At present, although there is a small amount of NMN in food, the content is too low to meet the needs of the human body.

There are specialized NMN supplements on the market. How to identify the true and the content of these supplements difference, choose the most appropriate own NMN supplements is also a subject that is worth our learning.

As a new potential solution for anti-aging and metabolic health, NMN has achieved remarkable results in animal experiments.

In the future, we look forward to more research progress on NMN in order to better understand its mechanism of action and apply it to real life to bring greater well-being to human health.

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